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Retatrutide, also known by its research code LY3437943, is a novel peptide that has garnered significant attention. It functions as a triple agonist, targeting the glucagon receptor (GCGR), glucagon-like peptide-1 receptor (GLP-1R), and glucose-dependent insulinotropic polypeptide receptor (GIP). This multi-receptor activation is believed to contribute to its potent effects on weight loss and metabolic regulation.Effects of once-weekly subcutaneous retatrutide on weight and metabolic ... Preliminary studies, including those that have been currently undergoing Phase 3 clinical trials (NCT05882045), suggest promising outcomes.

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