mt3 peptide Binds heavy metals - mt2-peptide-before-and-after is a representative zinc binding protein predominant in the brain The Multifaceted Nature of MT3 Peptide: A Deep Dive into Metallothionein-3

adhd-peptide The mt3 peptide, more formally known as Metallothionein-3 (MT3), is a fascinating and complex protein with significant implications across various biological contextsMetallothionein 3 (MT3) Antibody is a Rabbit polyclonal antibody against Mouse Metallothionein 3 (MT3).. This 68-amino acid peptide plays a crucial role, particularly within the nervous system, and its dysregulation has been linked to several neurological conditions.作者：L Ren·2018·被引用次数：3—Thepeptidecould be useful to evaluate the distribution and expression ofMT3-MMP. Furthermore, thepeptide-functionalized QDs show potential application for ... Understanding the intricate functions and characteristics of MT3 is vital for advancing our knowledge in areas ranging from neurobiology to potential therapeutic interventions.

MT3 is a member of the metallothionein family of proteins, distinguished by its high cysteine content and its exclusive expression in neural tissue. This unique characteristic positions MT3 as a key player in neuronal metal homeostasis. Research indicates that MT3 possesses a remarkable capacity to bind heavy metals, specifically showing an affinity for zinc and copper atoms. Typically, a single MT3 polypeptide chain can bind approximately three zinc and three copper atoms, with only a negligible amount of cadmium. This metal-binding capability is central to its biological functions, including its role as an antioxidant enzyme expressed exclusively in neural tissue.

The significance of MT3 in brain health is underscored by its abnormal under-expression in the brains of individuals suffering from Alzheimer's disease. This observation highlights the potential protective role of MT3 against neurodegenerative processes. Furthermore, studies have demonstrated that Zn 7 MT3 complexes can significantly ameliorate cognitive deficits, regulate metal homeostasis, abolish amyloid-beta (Aβ) plaque load, and reduce neuronal damage. This suggests that maintaining adequate levels and proper function of MT3 could be a therapeutic strategy for conditions characterized by cognitive decline.

Beyond its neuroprotective functions, MT3 also exhibits other intriguing propertiesMT3 / Metallothionein 3. It is recognized as a Protein Coding gene and has been implicated in cellular processes beyond its primary neural role. For instance, MT3 has been identified as an arsenic- and hypoxia-upregulated oncogene that promotes cell growth and invasion in bladder carcinoma cells by downregulating NDRG1 and NDRG2Metallothionein III (Mt3) is defined asan antioxidant enzyme expressed exclusively in neural tissue, involved in regulating zinc sequestration, .... This dual role, acting as both a protective agent in the brain and a potential promoter of cancer cell proliferation in other contexts, underscores the complexity of MT3's biological activity.

The MT3 peptide exists as a small protein with a molecular mass of approximately 7 kDa. Its structure and function have been extensively studied, leading to the development of various research toolsMetallothionein 3 (MT3) Antibody is a Rabbit polyclonal antibody against Mouse Metallothionein 3 (MT3).. Recombinant Mouse Metallothionein-3 (Mt3) and MT3 human Fusion Protein GST are examples of such tools, allowing researchers to investigate the protein's behavior in controlled laboratory settings. These recombinant proteins, often expressed from systems like *E2025年11月19日—The entireMT3 peptideshows a high capacity to bind Cu(+) , provided that this occurs in a nonoxidative milieux. This reflects a peculiar .... coli*, provide high purity and are instrumental in understanding the protein's interactions and activities.

The search intent surrounding mt3 peptide reveals a broad interest in its fundamental properties, its role in disease, and its potential applications. Keywords such as "68-amino acid peptide," "Binds heavy metals," and "Contains three zinc and three copper atoms per polypeptide chain" point to a need for detailed biochemical information. The mention of "an antioxidant enzyme expressed exclusively in neural tissue" and "is a representative zinc binding protein predominant in the brain" emphasizes its neurological significance. Furthermore, the inclusion of terms like "MT3 is an arsenic- and hypoxia-upregulated oncogene" and "Zn 7 MT3 can significantly ameliorate cognitive deficits" indicates interest in its involvement in both oncogenesis and neurodegenerative conditions.

While primarily known for its role in the central nervous system (CNS), the broader implications of MT3 are still being explored. Research on its expression patterns reveals its selective expression in the CNS, most abundant in astrocytesMuscarinic Toxin 3 | PEPTIDE INSTITUTE, INC.. However, the role of MT3 in other organs is an ongoing area of investigation. The study of MT3 also extends to its interaction with other molecules, such as the matrix metalloproteinases (MMPs). For instance, the peptide could be useful to evaluate the distribution and expression of MT3-MMP (MMP-16), a member of a family of peptidase enzymes responsible for degrading extracellular matrix components.MT3 human Fusion Protein GSTfrom Proteintech. Produced in E.coli-derived, PET28a, with high quality purity. Cat.No. Ag2823.

In summary, the mt3 peptide, or Metallothionein-3, is a vital protein with a multifaceted biological profile. Its potent metal-binding capacity, antioxidant properties, and selective expression in neural tissue make it a critical factor in maintaining brain health and function.作者：J Bousleiman·2017·被引用次数：31—This study focused on gaining a better understanding ofMT3metalloneurochemistry by examining relationships betweenMt3/Mt2 and known zinc homeostasis gene ... While its role in neuroprotection and its potential therapeutic benefits in conditions like Alzheimer's disease are well-documented, its involvement in oncogenesis and its broader physiological functions continue to be subjects of active research. The availability of recombinant MT3 and related reagents further facilitates these investigations, promising deeper insights into this essential peptide.Metallothionein 3 (MT3) Antibody